The study, published in June in eBioMedicine, conducted on animals, sheds light on a biological mechanism involved. Semaglutide i.e. Ozempic affected the brain's reward circuit, specifically the nucleus accumbens, which is part of the limbic system. "Alcohol activates the brain's reward system, which leads to the release of dopamine, a phenomenon observed in both humans and animals," explains co-author Cajsa Aranäs of the University of Gothenburg.